A teenaged girl is fighting for her life at SickKids Hospital after a three-vehicle crash west of Orangeville Wednesday afternoon.

It happened on Highway 9 between 7th Line and 8th Line of Amaranth Township around 3 p.m.

Police said a Chrysler Intrepid carrying three teens was travelling west when it crossed over the centre line, striking the rear of a Toyota Prius before colliding head-on with a Kia Optima Sedan.

The 17-year-old girl from the Chrysler was airlifted to hospital with serious, life-threatening injuries, OPP said. Her leg was also broken in the crash.

Three other people – one from the Kia and two teens inside the Intrepid – were taken to hospital with non-life-threatening injuries.

The driver of the Prius was not injured.

The circumstances leading up to the crash weren’t immediately clear.

Police said officers at the hospital are interviewing the injured to try and determine why the Intrepid crossed over the centre lane of the highway.

It does not appear that alcohol was a factor in the crash, police said. Officers are looking into whether excessive speed may have a played a role in the crash.

No charges have been laid.

A stretch of Highway 9 is expected to remain closed until around midnight as officers investigate the collision